Pharma's newest obsession involves mimicking the system that keeps people awake

The impoverished country is struggling to cope with the damage from two nearly simultaneous shocks

He has defied America twice in recent days

What happens if America quits

We calculate the drag on growth from fitful presidential policymaking

By continuously improving the iPhone, expanding its range and selling it in more places, Mr Cook built an empire.

The megastar's uncancellable songs are his rightful memorial

But it highlights longstanding tensions that the Gulf war has exacerbated

Prices, debt, and scarcity will strike a blow against the world's workshop

Many shipping routes are vulnerable, from the Strait of Malacca to the Panama Canal