The road from Damascus to Washington runs through Riyadh

The Riyadh summit marked a definitive break with decades of American sanctions on—and political isolation of—Syria

The road from Damascus to Washington runs through Riyadh

US President Donald Trump’s visit to Riyadh marked a historic turning point—one destined to be etched into the annals of diplomacy as a moment of lasting consequence for the Middle East and the formation of a new global order. Its significance lay in the breadth of accords it produced—spanning economic, defence, and scientific domains, and extending to groundbreaking agreements in artificial intelligence.

Yet the most striking development came with Trump’s unexpected announcement: the lifting of long-standing US sanctions on Syria and the restoration of diplomatic relations. This was swiftly followed by a landmark meeting with Syrian President Ahmed al-Sharaa, held under the patronage and with the backing of Saudi Crown Prince Mohammed bin Salman. The message was unmistakable: Damascus’s exit from the isolation long imposed by Washington now runs through Riyadh—a capital whose regional and global weight has become indisputable.

The Riyadh summit marked a definitive break with decades of American sanctions on—and political isolation of Syria— ostensibly in response to the former regime’s repression of its people, its antagonism towards neighbouring states, and its entrenchment in divisive regional alliances. The fall of the Assad regime at the end of last year was not merely a political transition; it was a strategic shift of historic proportions—arguably the most consequential event in the Middle East in recent decades.

Unlike Iraq, where the fall of Saddam Hussein in 2003 paved the way for the rise of the Iranian Crescent, the collapse of Assad’s rule in 2024 delivered a severe blow to that very arc of influence. And just as Syria’s alliance with Tehran had once tilted the regional balance towards the so-called “Axis of Resistance,” its return to the Arab fold now signals a profound recalibration of regional power.

By virtue of its geography, history, and latent potential, Syria is integral to the architecture of a reimagined regional order

A key cog in a new regional order

By virtue of its geography, history, and latent potential, Syria is integral to the architecture of a reimagined regional order and the reconstitution of Arab political relations. One could rightly say that it is a cornerstone in the emerging edifice of a new Middle East. For Iran, this realignment represents its greatest strategic loss since the 1979 revolution and its decades-long partnership with the Assad dynasty. And the consolidation of this setback—for Tehran—begins, unequivocally, in Damascus.

Tehran had long wagered on the persistence of sanctions and economic siege, anticipating that sustained pressure would push Syria towards implosion, chaos, and the resurgence of the Islamic State (IS)—offering Iran a chance to reclaim fragments of its waning influence. To forestall such a scenario, the only viable course lies in fostering stability through Syria's economic revitalisation and the removal of suffocating sanctions placed on it.

To be sure, the road to a 'new Syria' remains arduous. Much depends on clarifying the scope and mechanics of sanctions relief, as well as mobilising the immense resources required for reconstruction. Yet the most decisive step—the political will to dismantle the sanctions regime—has already been taken. In his decision, President Trump has set in motion a path for Syria to prosper or what he described as "a chance at greatness".

The file now lies with Syrian and American negotiators. Washington has outlined a set of demands for Damascus: the deportation of foreign fighters, serious commitments to counter-terrorism and the defeat of IS, the expulsion of Palestinian factions once instrumentalised by the previous regime, the destruction of remaining chemical weapons, and the eventual accession to peace agreements with Israel.

Today, Syria finds itself at a crossroads. One road leads towards sanctions relief. The other, in the event of sluggish US engagement, could lead to renewed crisis.

Damascus, in turn, has made clear its expectations: assistance in reasserting sovereignty over its full territory, technical cooperation in dismantling chemical stockpiles, support for restoring security in southern Syria, curbing Israeli incursions, and enhanced intelligence-sharing in the ongoing fight against IS.

At a crossroads

Today, Syria finds itself at a crossroads, racing between two divergent tracks. One leads towards sanctions relief, the resumption of reconstruction, and the consolidation of stability within Syria and across the region. The other is marked by the sluggish pace of American engagement, bureaucratic inertia, and the risk of renewed crises spilling beyond Syria's borders.

It is manifestly in the interest of Syria, its neighbours, and the broader Middle East to ensure the success of the first path—and this historic moment demands it be pursued with urgency.

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