BioNTech

Last year's 12-day war with Iran was ostensibly aimed at its nuclear programme. This time, the regime is significantly weakened, presenting an opportunity Israel may feel it can't miss.

Pressure builds on Venezuela after Trump appoints himself 'acting president'. With Colombia, Mexico and Cuba seemingly also in the line of fire, they will be closely watching what happens in Caracas.

It remains unclear if Damascus's move to kick the Kurds out of Aleppo will pressure the SDF to implement the 10 March deal to integrate its forces into the Syrian army or harden its resolve to resist

The UAE backs southern Yemenis who want secession, while Saudi Arabia wants a unified Yemen. Egypt also favours unity, but is close to both Gulf states, putting it in a difficult position.

Recently declassified meeting minutes between the two leaders show how Washington was well aware of Moscow's grievances over NATO expansion, but went ahead anyway